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Murine Retrovirally-transduced Bone Marrow Engraftment Models of MLL-fusion-driven Acute Myelogenous Leukemias (AML)

MLL-rearranged leukemia represents approximately 5-10% of adult AML cases and nearly half of all infant/pediatric acute leukemia cases. These leukemias have a poor prognosis, and as of yet there are no approved targeted therapeutic options. The rearrangement in the MLL gene leads to aberrant express...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Protoc Pharmacol
Main Authors: Stubbs, Matthew C., Krivtsov, Andrei V.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658028/
https://ncbi.nlm.nih.gov/pubmed/28892146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpph.28
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