Integrated STAT3 and Ikaros Zinc Finger transcription factor activities regulate Bcl-6 expression in CD4(+) T helper cells

Bcl-6 (B cell lymphoma-6) is a transcriptional repressor required for the differentiation of T follicular helper (T(FH)) cell populations. Currently, the molecular mechanisms underlying the transcriptional regulation of Bcl-6 expression are unclear. Here, we have identified the Ikaros zinc finger (I...

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Gepubliceerd in:J Immunol
Hoofdauteurs: Read, Kaitlin A., Powell, Michael D., Baker, Chandra E., Sreekumar, Bharath K., Ringel-Scaia, Veronica M., Bachus, Holly, Martin, R. Emily, Cooley, Ian D., Allen, Irving C., Ballesteros-Tato, Andre, Oestreich, Kenneth J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657606/
https://ncbi.nlm.nih.gov/pubmed/28848064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700106
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