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Anti-tumor antibodies can drive therapeutic T cell responses

The classical view of therapeutic monoclonal antibodies against tumor associated antigens is that their mechanism of action is dominated by signal blocking or the cytotoxicity of Fc-driven innate immune effector functions. We review here a mounting body of evidence that anti-TAA mAbs are capable of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Cancer
Prif Awdur: Wittrup, K. Dane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657573/
https://ncbi.nlm.nih.gov/pubmed/28867165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.07.001
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