Structural and functional impacts of ER coactivator sequential recruitment

Nuclear receptors recruit multiple coactivators sequentially to activate transcription. This “ordered” recruitment allows different coactivator activities to engage the nuclear receptor complex at different steps of transcription. Estrogen receptor (ER) recruits SRC-3 primary coactivator and seconda...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Yi, Ping, Wang, Zhao, Feng, Qin, Chou, Chao-Kai, Pintilie, Grigore D., Shen, Hong, Foulds, Charles E., Fan, Guizhen, Serysheva, Irina, Ludtke, Steven J., Schmid, Michael F., Hung, Mien-Chie, Chiu, Wah, O’Malley, Bert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657569/
https://ncbi.nlm.nih.gov/pubmed/28844863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.026
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