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Small-Molecule PET Tracers for Imaging Proteinopathies

In this chapter, we provide a review of the challenges and advances in developing successful positron emission tomography (PET) imaging agents for three major types of aggregated amyloid proteins – amyloid-beta (Aβ), tau, and alpha-synuclein (α-syn). These three amyloids are involved in the pathogen...

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Detalles Bibliográficos
Publicado en:Semin Nucl Med
Main Authors: Mathis, Chester A., Lopresti, Brian J., Ikonomovic, Milos D., Klunk, William E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657567/
https://ncbi.nlm.nih.gov/pubmed/28826526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.semnuclmed.2017.06.003
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