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Improving somatic variant identification through integration of genome and exome data

BACKGROUND: Cost-effective high-throughput sequencing technologies, together with efficient mapping and variant calling tools, have made it possible to identify somatic variants for cancer study. However, integrating somatic variants from whole exome and whole genome studies poses a challenge to res...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Vijayan, Vinaya, Yiu, Siu-Ming, Zhang, Liqing
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657037/
https://ncbi.nlm.nih.gov/pubmed/29513195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4134-3
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