The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A

Transcription factor 4 (TCF4 also known as ITF2 or E2-2) is a basic helix-loop-helix (bHLH) protein associated with Pitt–Hopkins syndrome, intellectual disability, and schizophrenia (SCZ). Here, we show that TCF4-dependent transcription in cortical neurons cultured from embryonic rats of both sexes...

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Publicat a:J Neurosci
Autors principals: Sepp, Mari, Vihma, Hanna, Nurm, Kaja, Urb, Mari, Page, Stephanie Cerceo, Roots, Kaisa, Hark, Anu, Maher, Brady J., Pruunsild, Priit, Timmusk, Tõnis
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656997/
https://ncbi.nlm.nih.gov/pubmed/28951451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1151-17.2017
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