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Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless
Pitt-Hopkins syndrome (PTHS) is caused by haploinsufficiency of Transcription factor 4 (TCF4), one of the three human class I basic helix-loop-helix transcription factors called E-proteins. Drosophila has a single E-protein, Daughterless (Da), homologous to all three mammalian counterparts. Here we...
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| Publicado no: | Biol Open |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736037/ https://ncbi.nlm.nih.gov/pubmed/26621827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.014696 |
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