A Cross Talk between Neuronal Urokinase-type Plasminogen Activator (uPA) and Astrocytic uPA Receptor (uPAR) Promotes Astrocytic Activation and Synaptic Recovery in the Ischemic Brain

Urokinase-type plasminogen activator (uPA) is a serine proteinase that, upon binding to its receptor (uPAR), catalyzes the conversion of plasminogen into plasmin on the cell surface. Our previous studies indicate that uPA and uPAR expression increase in the ischemic brain during the recovery phase f...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Diaz, Ariel, Merino, Paola, Manrique, Luis Guillermo, Ospina, Juan Pablo, Cheng, Lihong, Wu, Fang, Jeanneret, Valerie, Yepes, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2017
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656992/
https://ncbi.nlm.nih.gov/pubmed/28931568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1630-17.2017
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