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Phe354Leu Polymorphism of LKB1 Is a Potential Prognostic Factor for Cytogenetically Normal Acute Myeloid Leukemia

Background/Aim: Liver kinase B1 (LKB1) is a major activator of the AMP-dependent kinase/mammalian target of rapamycin pathway. The prevalence and the specificity of LKB1 gene mutation in acute myeloid leukemia (AML) have not been well established. This study aimed to examine mutation of LKB1 in AML...

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Publicat a:In Vivo
Autors principals: YANG, MING-YU, HSIAO, HUI-HUA, LIU, YI-CHANG, HSU, CHENG-MING, LIN, SHENG-FUNG, LIN, PAI-MEI
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656856/
https://ncbi.nlm.nih.gov/pubmed/28882949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11137
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