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Phe354Leu Polymorphism of LKB1 Is a Potential Prognostic Factor for Cytogenetically Normal Acute Myeloid Leukemia

Background/Aim: Liver kinase B1 (LKB1) is a major activator of the AMP-dependent kinase/mammalian target of rapamycin pathway. The prevalence and the specificity of LKB1 gene mutation in acute myeloid leukemia (AML) have not been well established. This study aimed to examine mutation of LKB1 in AML...

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Detalhes bibliográficos
Publicado no:In Vivo
Main Authors: YANG, MING-YU, HSIAO, HUI-HUA, LIU, YI-CHANG, HSU, CHENG-MING, LIN, SHENG-FUNG, LIN, PAI-MEI
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656856/
https://ncbi.nlm.nih.gov/pubmed/28882949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11137
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