Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition. We applied an integrated proteomic and genetic strategy by targeting a tandem affinity purification (TAP) tag and Venus fluorescen...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Fernández, Esperanza, Collins, Mark O., Frank, René A.W., Zhu, Fei, Kopanitsa, Maksym V., Nithianantharajah, Jess, Lemprière, Sarah A., Fricker, David, Elsegood, Kathryn A., McLaughlin, Catherine L., Croning, Mike D.R., Mclean, Colin, Armstrong, J. Douglas, Hill, W. David, Deary, Ian J., Cencelli, Giulia, Bagni, Claudia, Fromer, Menachem, Purcell, Shaun M., Pocklington, Andrew J., Choudhary, Jyoti S., Komiyama, Noboru H., Grant, Seth G.N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656750/
https://ncbi.nlm.nih.gov/pubmed/29045836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.045
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