An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques

Women globally need access to multipurpose prevention technologies (MPTs) that prevent human immunodeficiency virus (HIV), sexually transmitted infections that increase HIV acquisition/transmission risk, and unintended pregnancy. Seeking an MPT with activity against HIV, herpes simplex virus-2 (HSV-...

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Publicado en:Drug Deliv Transl Res
Autores principales: Derby, Nina, Aravantinou, Meropi, Kenney, Jessica, Ugaonkar, Shweta R., Wesenberg, Asa, Wilk, Jolanta, Kizima, Larisa, Rodriguez, Aixa, Zhang, Shimin, Mizenina, Olga, Levendosky, Keith, Cooney, Michael L., Seidor, Samantha, Gettie, Agegnehu, Grasperge, Brooke, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Fernández-Romero, José, Zydowsky, Thomas M., Robbiani, Melissa
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656733/
https://ncbi.nlm.nih.gov/pubmed/28600625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0389-0
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