An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques

Women globally need access to multipurpose prevention technologies (MPTs) that prevent human immunodeficiency virus (HIV), sexually transmitted infections that increase HIV acquisition/transmission risk, and unintended pregnancy. Seeking an MPT with activity against HIV, herpes simplex virus-2 (HSV-...

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Vydáno v:Drug Deliv Transl Res
Hlavní autoři: Derby, Nina, Aravantinou, Meropi, Kenney, Jessica, Ugaonkar, Shweta R., Wesenberg, Asa, Wilk, Jolanta, Kizima, Larisa, Rodriguez, Aixa, Zhang, Shimin, Mizenina, Olga, Levendosky, Keith, Cooney, Michael L., Seidor, Samantha, Gettie, Agegnehu, Grasperge, Brooke, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Fernández-Romero, José, Zydowsky, Thomas M., Robbiani, Melissa
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656733/
https://ncbi.nlm.nih.gov/pubmed/28600625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0389-0
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