Synthesis and preliminary assessment of the anticancer and Wnt/β-catenin inhibitory activity of small amide libraries of fenamates and profens

As part of an ongoing program to study the anticancer activity of non-steroidal anti-inflammatory drugs (NSAIDs) through generating diversity libraries of multiple NSAID scaffolds, we synthesized a series of NSAID amide derivatives and screened these sets against three cancer cell lines (prostate, c...

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Bibliographic Details
Published in:Med Chem Res
Main Authors: Mathew, Bini, Hobrath, Judith V., Lu, Wenyan, Li, Yonghe, Reynolds, Robert C.
Format: Artigo
Language:Inglês
Published: Springer US 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656725/
https://ncbi.nlm.nih.gov/pubmed/29104411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-017-2001-z
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