Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

In stroke patients, loss of skeletal muscle mass leads to prolonged weakness and less efficient rehabilitation. We previously showed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly increased in skeletal muscle in a mouse model of stroke. We therefore t...

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Publicado en:Sci Rep
Autores principales: Desgeorges, Marine Maud, Devillard, Xavier, Toutain, Jérome, Castells, Josiane, Divoux, Didier, Arnould, David Frédéric, Haqq, Christopher, Bernaudin, Myriam, Durieux, Anne-Cécile, Touzani, Omar, Freyssenet, Damien Gilles
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656661/
https://ncbi.nlm.nih.gov/pubmed/29070788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13912-0
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