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dOCRL maintains immune cell quiescence by regulating endosomal traffic
Lowe Syndrome is a developmental disorder characterized by eye, kidney, and neurological pathologies, and is caused by mutations in the phosphatidylinositol-5-phosphatase OCRL. OCRL plays diverse roles in endocytic and endolysosomal trafficking, cytokinesis, and ciliogenesis, but it is unclear which...
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Publicado no: | PLoS Genet |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656325/ https://ncbi.nlm.nih.gov/pubmed/29028801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007052 |
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