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Forkhead Box Transcription Factors of the FOXA Class Are Required for Basal Transcription of Angiotensin-Converting Enzyme 2

Angiotensin-converting enzyme 2 (ACE2) has protective effects on a wide range of morbidities associated with elevated angiotensin-II signaling. Most tissues, including pancreatic islets, express ACE2 mainly from the proximal promoter region. We previously found that hepatocyte nuclear factors 1α and...

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Vydáno v:J Endocr Soc
Hlavní autoři: Pedersen, Kim Brint, Chodavarapu, Harshita, Lazartigues, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656262/
https://ncbi.nlm.nih.gov/pubmed/29082356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2016-1071
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