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Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays

Angiotensin-converting enzyme 2 (ACE2) is a component of the renin-angiotensin system, and its expression and activity have been shown to be reduced in cardiovascular diseases. Enzymatic activity of ACE2 is commonly measured by hydrolysis of quenched fluorescent substrates in the absence or presence...

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Detalhes bibliográficos
Main Authors: Pedersen, Kim Brint, Sriramula, Srinivas, Chhabra, Kavaljit H., Xia, Huijing, Lazartigues, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213941/
https://ncbi.nlm.nih.gov/pubmed/21880865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00339.2011
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