IQGAP2 is a novel interferon-alpha antiviral effector gene acting nonconventionally through the NF-κB pathway

BACKGROUND & AIMS: Type I interferons (IFN) provide the first line of defense against invading pathogens but its mechanism of action is still not well understood. Using unbiased genome-wide siRNA screens, we recently identified IQ-motif containing GTPase activating protein 2 (IQGAP2), a tumor su...

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Publicado en:J Hepatol
Main Authors: Brisac, Cynthia, Salloum, Shadi, Yang, Victor, Schaefer, Esperance AK, Holmes, Jacinta A, Chevaliez, Stephane, Hong, Jian, Carlton-Smith, Charlie, Alatrakchi, Nadia, Kruger, Annie, Lin, Wenyu, Chung, Raymond T
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656012/
https://ncbi.nlm.nih.gov/pubmed/27401546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.06.028
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