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Processive searching ability varies among members of the gap-filling DNA polymerase X family

DNA repair proteins must locate rare damaged sites within the genome. DNA polymerase β (Pol β), a member of the DNA polymerase X family that is involved in base excision repair, uses a processive hopping search mechanism to locate substrates. This effectively enhances its search footprint on DNA, in...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Howard, Michael J., Wilson, Samuel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655522/
https://ncbi.nlm.nih.gov/pubmed/28893909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801860
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