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DNA polymerase β uses its lyase domain in a processive search for DNA damage
DNA polymerase (Pol) β maintains genome fidelity by catalyzing DNA synthesis and removal of a reactive DNA repair intermediate during base excision repair (BER). Situated within the middle of the BER pathway, Pol β must efficiently locate its substrates before damage is exacerbated. The mechanisms o...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397181/ https://ncbi.nlm.nih.gov/pubmed/28119421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx047 |
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