Improving the thermal stability of cellobiohydrolase Cel7A from Hypocrea jecorina by directed evolution

Secreted mixtures of Hypocrea jecorina cellulases are able to efficiently degrade cellulosic biomass to fermentable sugars at large, commercially relevant scales. H. jecorina Cel7A, cellobiohydrolase I, from glycoside hydrolase family 7, is the workhorse enzyme of the process. However, the thermal s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Goedegebuur, Frits, Dankmeyer, Lydia, Gualfetti, Peter, Karkehabadi, Saeid, Hansson, Henrik, Jana, Suvamay, Huynh, Vicky, Kelemen, Bradley R., Kruithof, Paulien, Larenas, Edmund A., Teunissen, Pauline J. M., Ståhlberg, Jerry, Payne, Christina M., Mitchinson, Colin, Sandgren, Mats
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Enzymology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655518/
https://ncbi.nlm.nih.gov/pubmed/28860192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.803270
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