The preclinical analysis of TW-37 as a potential anti-colorectal cancer cell agent

TW-37 is a novel, potent and non-peptide Bcl-2 small-molecule inhibitor. Its activity in colorectal cancer (CRC) cells is studied. In both HCT-116 cells and primary human colon cancer cells, treatment with TW-37 at only nM concentration efficiently inhibited cell survival and proliferation. TW-37 al...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Lei, Shun, Ding, Yao, Fu, Yun, Wu, Shuang, Xie, Xiong, Wang, Cancan, Liang, Houjie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655484/
https://ncbi.nlm.nih.gov/pubmed/29065135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184501
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