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Preclinical study of cinobufagin as a promising anti-colorectal cancer agent

Here, we assessed the anti-colorectal cancer (CRC) cell activity of cinobufagin (CBG). We found that CBG exerted potent cytotoxic and anti-proliferative activity against CRC lines (HCT-116 and HT-29) and primary human CRC cells. Meanwhile, it activated apoptosis, and disrupted cell-cycle progression...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Lu, Xing-sheng, Qiao, Yin-biao, Li, Ya, Yang, Bo, Chen, Min-bin, Xing, Chun-gen
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352212/
https://ncbi.nlm.nih.gov/pubmed/27894091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13519
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