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Drosophila VAMP7 regulates Wingless intracellular trafficking

Drosophila Wingless (Wg) is a morphogen that determines cell fate during development. Previous studies have shown that endocytic pathways regulate Wg trafficking and signaling. Here, we showed that loss of vamp7, a gene required for vesicle fusion, dramatically increased Wg levels and decreased Wg s...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Gao, Han, He, Fang, Lin, Xinhua, Wu, Yihui
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655445/
https://ncbi.nlm.nih.gov/pubmed/29065163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186938
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