Simultaneous silencing of TGF-β1 and COX-2 reduces human skin hypertrophic scar through activation of fibroblast apoptosis

Excessive skin scars due to elective operations or trauma represent a challenging clinical problem. Pathophysiology of hypertrophic scars entails a prolonged inflammatory and proliferative phase of wound healing. Over expression of TGF-β1 and COX-2 play key regulatory roles of the aberrant fibrogeni...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Zhou, Jia, Zhao, Yixuan, Simonenko, Vera, Xu, John J., Liu, Kai, Wang, Deling, Shi, Jingli, Zhong, Tianyi, Zhang, Lixia, Zeng, Lun, Huang, Bin, Tang, Shenggao, Lu, Alan Y., Mixson, A. James, Sun, Yangbai, Lu, Patrick Y., Li, Qingfeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655228/
https://ncbi.nlm.nih.gov/pubmed/29113333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20869
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