Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling

Inflammatory responses play crucial roles in cerebral ischemia/reperfusion injury. Toll-like receptor 4 (TLR4) is an important mediator of the neuroinflammatory response to cerebral ischemia/reperfusion injury. Vinpocetine is a derivative of the alkaloid vincamine and exerts an anti-inflammatory eff...

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Udgivet i:Oncotarget
Main Authors: Wu, Li-Rong, Liu, Liang, Xiong, Xiao-Yi, Zhang, Qin, Wang, Fa-Xiang, Gong, Chang-Xiong, Zhong, Qi, Yang, Yuan-Rui, Meng, Zhao-You, Yang, Qing-Wu
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655200/
https://ncbi.nlm.nih.gov/pubmed/29113305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20699
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