IL-8, GRO and MCP-1 produced by hepatocellular carcinoma microenvironment determine the migratory capacity of human bone marrow-derived mesenchymal stromal cells without affecting tumor aggressiveness

New therapies are needed for advanced hepatocellular carcinoma (HCC) and the use of mesenchymal stromal cells (MSCs) carrying therapeutic genes is a promising strategy. HCC produce cytokines recruiting MSCs to the tumor milieu and modifying its biological properties. Our aim was to study changes gen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bayo, Juan, Real, Alejandrina, Fiore, Esteban J., Malvicini, Mariana, Sganga, Leonardo, Bolontrade, Marcela, Andriani, Oscar, Bizama, Carolina, Fresno, Cristóbal, Podhajcer, Osvaldo, Fernandez, Elmer, Gidekel, Manuel, Mazzolini, Guillermo D., García, Mariana G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655193/
https://ncbi.nlm.nih.gov/pubmed/29113298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10288
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