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Transcription of a 5’ extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter
Cell differentiation programs require dynamic regulation of gene expression. During meiotic prophase in Saccharomyces cerevisiae, expression of the kinetochore complex subunit Ndc80 is downregulated by a 5’ extended long undecoded NDC80 transcript isoform. Here we demonstrate a transcriptional inter...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655139/ https://ncbi.nlm.nih.gov/pubmed/28906248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27420 |
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