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Immunodeficiency and Intermittent Dosing Promote Acquired Rifamycin Monoresistance in Murine Tuberculosis

More-permissive preclinical models may be useful in evaluating antituberculosis regimens for their propensity to select drug-resistant mutants. To evaluate whether acquired rifamycin monoresistance could be recapitulated in mice and, if so, to evaluate the effects of immunodeficiency, intermittent d...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Park, Sang-Won, Tasneen, Rokeya, Converse, Paul J., Nuermberger, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655103/
https://ncbi.nlm.nih.gov/pubmed/28874368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01502-17
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