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Population Pharmacokinetics of Posaconazole Tablets and Monte Carlo Simulations To Determine whether All Patients Should Receive the Same Dose

Posaconazole is extensively used for prophylaxis for invasive fungal infections. The gastro-resistant tablet formulation has allowed the bioavailability issues encountered with the oral suspension to be overcome. However, overexposure is now frequent. This study aimed to (i) describe the pharmacokin...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Petitcollin, A., Boglione-Kerrien, C., Tron, C., Nimubona, S., Lalanne, S., Lemaitre, F., Bellissant, E., Verdier, M.-C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655095/
https://ncbi.nlm.nih.gov/pubmed/28848009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01166-17
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