Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae

Clarithromycin-resistant Haemophilus influenzae strains with a nonsense mutation in acrR generally exhibited susceptibility to azithromycin, although one strain was found to be nonsusceptible; we aimed to clarify the differences. This strain had an amino acid substitution, Arg327Ser, in AcrB. Introd...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Seyama, Shoji, Wajima, Takeaki, Nakaminami, Hidemasa, Noguchi, Norihisa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655073/
https://ncbi.nlm.nih.gov/pubmed/28848006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01337-17
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars