Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae

Clarithromycin-resistant Haemophilus influenzae strains with a nonsense mutation in acrR generally exhibited susceptibility to azithromycin, although one strain was found to be nonsusceptible; we aimed to clarify the differences. This strain had an amino acid substitution, Arg327Ser, in AcrB. Introd...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Seyama, Shoji, Wajima, Takeaki, Nakaminami, Hidemasa, Noguchi, Norihisa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655073/
https://ncbi.nlm.nih.gov/pubmed/28848006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01337-17
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