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Clarithromycin Resistance Mechanisms of Epidemic β-Lactamase-Nonproducing Ampicillin-Resistant Haemophilus influenzae Strains in Japan

The aim of this study was to clarify the clarithromycin resistance mechanisms of β-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae strains. In all clarithromycin-resistant strains, the transcript level of acrB was significantly elevated, and these strains had a frameshift mutation...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Seyama, Shoji, Wajima, Takeaki, Nakaminami, Hidemasa, Noguchi, Norihisa
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862528/
https://ncbi.nlm.nih.gov/pubmed/26953210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00163-16
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