Mycobacterium tuberculosis Subculture Results in Loss of Potentially Clinically Relevant Heteroresistance

Multidrug-resistant tuberculosis (TB) presents a major public health dilemma. Heteroresistance, the coexistence of drug-resistant and drug-susceptible strains or of multiple drug-resistant strains with discrete haplotypes, may affect accurate diagnosis and the institution of effective treatment. Sub...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Metcalfe, John Z., Streicher, Elizabeth, Theron, Grant, Colman, Rebecca E., Penaloza, Renee, Allender, Christopher, Lemmer, Darrin, Warren, Robin M., Engelthaler, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655066/
https://ncbi.nlm.nih.gov/pubmed/28893776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00888-17
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