The Global Regulatory Cyclic AMP Receptor Protein (CRP) Controls Multifactorial Fluoroquinolone Susceptibility in Salmonella enterica Serovar Typhimurium

Fluoroquinolone antibiotics are prescribed for the treatment of Salmonella enterica infections, but resistance to this family of antibiotics is growing. Here we report that loss of the global regulatory protein cyclic AMP (cAMP) receptor protein (CRP) or its allosteric effector, cAMP, reduces suscep...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Kary, Stefani C., Yoneda, Joshua R. K., Olshefsky, Stephen C., Stewart, Laura A., West, Steven B., Cameron, Andrew D. S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655056/
https://ncbi.nlm.nih.gov/pubmed/28874380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01666-17
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