The Global Regulatory Cyclic AMP Receptor Protein (CRP) Controls Multifactorial Fluoroquinolone Susceptibility in Salmonella enterica Serovar Typhimurium

Fluoroquinolone antibiotics are prescribed for the treatment of Salmonella enterica infections, but resistance to this family of antibiotics is growing. Here we report that loss of the global regulatory protein cyclic AMP (cAMP) receptor protein (CRP) or its allosteric effector, cAMP, reduces suscep...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kary, Stefani C., Yoneda, Joshua R. K., Olshefsky, Stephen C., Stewart, Laura A., West, Steven B., Cameron, Andrew D. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655056/
https://ncbi.nlm.nih.gov/pubmed/28874380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01666-17
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