Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients

Rationale: Discordant alternans, a phenomenon in which the action potential duration (APDs) and/or intracellular calcium transient durations (CaDs) in different spatial regions of cardiac tissue are out of phase, present a dynamical instability for complex spatial dispersion that can be associated w...

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Publicat a:Front Physiol
Autors principals: Uzelac, Ilija, Ji, Yanyan C., Hornung, Daniel, Schröder-Scheteling, Johannes, Luther, Stefan, Gray, Richard A., Cherry, Elizabeth M., Fenton, Flavio H.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655020/
https://ncbi.nlm.nih.gov/pubmed/29104543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00819
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