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Tuning of the Lethal Response to Multiple Stressors with a Single-Site Mutation during Clinical Infection by Staphylococcus aureus

The agr system of Staphylococcus aureus promotes invasion of host tissues, and as expected, agents that block agr quorum sensing have anti-infective properties. Paradoxically, agr-defective mutants are frequently recovered from patients, especially those persistently infected with S. aureus. We foun...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Kumar, Krishan, Chen, John, Drlica, Karl, Shopsin, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654930/
https://ncbi.nlm.nih.gov/pubmed/29066545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01476-17
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