Mechanisms of CNS Viral Seeding by HIV(+) CD14(+) CD16(+) Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders

HIV reservoirs persist despite antiretroviral therapy (ART) and are established within a few days after infection. Infected myeloid cells in the central nervous system (CNS) may contribute to the establishment of a CNS viral reservoir. The mature CD14(+) CD16(+) monocyte subset enters the CNS in res...

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Veenstra, Mike, León-Rivera, Rosiris, Li, Ming, Gama, Lucio, Clements, Janice E., Berman, Joan W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654927/
https://ncbi.nlm.nih.gov/pubmed/29066542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01280-17
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