CCR2 on peripheral blood CD14(+)CD16(+) monocytes correlates with neuronal damage, HIV-associated neurocognitive disorders, and peripheral HIV DNA: reseeding of CNS reservoirs?

HIV-associated neurocognitive disorders (HAND) occur in ~50% of HIV infected individuals despite combined antiretroviral therapy. Transmigration into the CNS of CD14(+)CD16(+) monocytes, particularly those that are HIV infected and express increased surface chemokine receptor CCR2, contributes to ne...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Veenstra, Mike, Byrd, Desiree A., Inglese, Matilde, Buyukturkoglu, Korhan, Williams, Dionna W., Fleysher, Lazar, Li, Ming, Gama, Lucio, León-Rivera, Rosiris, Calderon, Tina M., Clements, Janice E., Morgello, Susan, Berman, Joan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320730/
https://ncbi.nlm.nih.gov/pubmed/29981000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-018-9792-7
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