In vitro and in vivo protein release and anti-ischemia/reperfusion injury properties of bone morphogenetic protein-2-loaded glycyrrhetinic acid-poly(ethylene glycol)-b-poly(l-lysine) nanoparticles

Here, we describe a bone morphogenetic protein-2 (BMP-2) nanocarrier based on glycyrrhetinic acid (GA)-poly(ethylene glycol) (PEG)-b-poly(l-lysine) (PLL). A protein nanocarrier was synthesized, characterized and evaluated as a BMP-2 delivery system. The designed nanocarrier was synthesized based on...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Shan, Fang, Liu, YuJuan, Jiang, Haiying, Tong, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654819/
https://ncbi.nlm.nih.gov/pubmed/29089759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S146546
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