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Preparation of exenatide-loaded linear poly(ethylene glycol)-brush poly(l-lysine) block copolymer: potential implications on diabetic nephropathy

The poly(ethylene glycol)-b-brush poly(l-lysine) polymer (PEG-b-(PELG(50)-g-PLL(3))) was synthesized and evaluated as a nanocarrier for prolonging delivery of exenatide through the abdominal subcutaneous injection route. The isoelectric point of exenatide was 4.86, and exenatide could combine with P...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Autor principal: Tong, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500490/
https://ncbi.nlm.nih.gov/pubmed/28721043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S136646
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