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Expanding perspectives on the significance of mitophagy in cancer

Mitophagy is a selective mode of autophagy in which mitochondria are specifically targeted for degradation at the autophagolysosome. Mitophagy is activated by stresses such as hypoxia, nutrient deprivation, DNA damage, inflammation and mitochondrial membrane depolarization and plays a role in mainta...

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Bibliografische gegevens
Gepubliceerd in:Semin Cancer Biol
Hoofdauteurs: Drake, Lauren E., Springer, Maya Z., Poole, Logan P., Kim, Casey J., Macleod, Kay F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654704/
https://ncbi.nlm.nih.gov/pubmed/28450176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.04.008
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