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Expanding perspectives on the significance of mitophagy in cancer

Mitophagy is a selective mode of autophagy in which mitochondria are specifically targeted for degradation at the autophagolysosome. Mitophagy is activated by stresses such as hypoxia, nutrient deprivation, DNA damage, inflammation and mitochondrial membrane depolarization and plays a role in mainta...

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Bibliographic Details
Published in:Semin Cancer Biol
Main Authors: Drake, Lauren E., Springer, Maya Z., Poole, Logan P., Kim, Casey J., Macleod, Kay F.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654704/
https://ncbi.nlm.nih.gov/pubmed/28450176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.04.008
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