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ECM turnover-stimulated gene delivery through collagen-mimetic peptide-plasmid integration in collagen
Gene therapies have great potential in regenerative medicine; however, clinical translation has been inhibited by low stability and limited transfection efficiencies. Herein, we incorporate collagen-mimetic peptide (CMP)-linked polyplexes in collagen scaffolds to increase DNA stability by up to 400%...
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| Опубликовано в: : | Acta Biomater |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654588/ https://ncbi.nlm.nih.gov/pubmed/28865990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.08.038 |
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