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ECM turnover-stimulated gene delivery through collagen-mimetic peptide-plasmid integration in collagen
Gene therapies have great potential in regenerative medicine; however, clinical translation has been inhibited by low stability and limited transfection efficiencies. Herein, we incorporate collagen-mimetic peptide (CMP)-linked polyplexes in collagen scaffolds to increase DNA stability by up to 400%...
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| Publicat a: | Acta Biomater |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654588/ https://ncbi.nlm.nih.gov/pubmed/28865990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.08.038 |
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