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Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity
BACKGROUND AND AIMS: Pannexins constitute a relatively new family of transmembrane proteins that form channels linking the cytoplasmic compartment with the extracellular environment. Presence of pannexin1 in the liver has been documented previously, where it underlies inflammatory responses, such as...
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Publicado no: | Arch Toxicol |
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Main Authors: | , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654513/ https://ncbi.nlm.nih.gov/pubmed/27826632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1885-6 |
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