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Molecular plasticity of the voltage-dependent anion channel embedded into a membrane

The voltage-dependent anion channel (VDAC) regulates the flux of metabolites and ions across the outer mitochondrial membrane. Regulation of ion flow involves conformational transitions in VDAC, but the nature of these changes has not been resolved to date. By combining single-molecule force experim...

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Bibliographic Details
Published in:Structure
Main Authors: Ge, Lin, Villinger, Saskia, Mari, Stefania A., Giller, Karin, Griesinger, Christian, Becker, Stefan, Müller, Daniel J., Zweckstetter, Markus
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654509/
https://ncbi.nlm.nih.gov/pubmed/27021164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.02.012
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