β-barrel mobility underlies closure of the voltage-dependent anion channel

The voltage-dependent anion channel (VDAC) is the major protein in the outer membrane of mitochondria, where it mediates efficient transport of ATP and ADP. Changes in its conformation and permeability, induced by voltage or apoptosis-related proteins, have been implicated in apoptotic pathways. The...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Zachariae, Ulrich, Schneider, Robert, Briones, Rodolfo, Gattin, Zrinka, Demers, Jean-Philippe, Giller, Karin, Maier, Elke, Zweckstetter, Markus, Griesinger, Christian, Becker, Stefan, Benz, Roland, de Groot, Bert L., Lange, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650048/
https://ncbi.nlm.nih.gov/pubmed/22841291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.06.015
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