β-barrel mobility underlies closure of the voltage-dependent anion channel

The voltage-dependent anion channel (VDAC) is the major protein in the outer membrane of mitochondria, where it mediates efficient transport of ATP and ADP. Changes in its conformation and permeability, induced by voltage or apoptosis-related proteins, have been implicated in apoptotic pathways. The...

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發表在:Structure
Main Authors: Zachariae, Ulrich, Schneider, Robert, Briones, Rodolfo, Gattin, Zrinka, Demers, Jean-Philippe, Giller, Karin, Maier, Elke, Zweckstetter, Markus, Griesinger, Christian, Becker, Stefan, Benz, Roland, de Groot, Bert L., Lange, Adam
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650048/
https://ncbi.nlm.nih.gov/pubmed/22841291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.06.015
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